Life Sciences Post-Translational Modification Analysis
Post-Translational Modifications (PTMs) analysis from SGS – identify a wide range of co- and post-translational modifications.
During or following the translation of the oligonucleotide message into an amino acid sequence, numerous modification events occur, activating the protein and enabling it to perform its function. Modifications include formation of disulfide bridges, cleavage of signal peptides and covalent modifications. These changes are not predictable from the gene sequence. So studying the expressed protein product to detect these modifications is vital.
We have developed strategies based on mass spectrometry (MS) and MS peptide mapping to detect and identify a wide range of co- and post-translational modifications. These include acetylation, phosphorylation, sulfation, as well as, perhaps most importantly for biopharmaceutical products, glycosylation.
Trusted post-translational modifications analysis from the leading provider
As the world’s leading provider of post-translational modifications analysis, we provide you with the experience, technical and regulatory expertise, and unique global network you need.
To find out more about our post-translational modifications service, contact us today.